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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e395eaa16e91c968bce8dffd3f61fc52e74be52ba4798094430c672914c2ea' 
  AND token = 'MNV7mv8nlDD1u0BCCuiVcFIdegJQPnrcLWKcuAcKeeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}