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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e41f6b2dc56afa5366db14477cc7271ca0b8dd1d4d2e2367572482ea31a4a40' 
  AND token = '8yx3A3py8kXrvEY0lfndXwnxCQdHnAMRcItXRRtPMmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}