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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc9e9983cdfa163e62589032fa784e1dc29b569b31238960e23ec93630deb3e' 
  AND token = 'VPPKLoouvFUalPx/bFje3HafFvbiQhDZ0h8U+IuAO/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}