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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ba2102a9712671e6511f976d639b8f2c82b121c06294c465b1dff9dd139364c' 
  AND token = 'D7em9G2dZM2VRBC3MLjRzxgE2dbnH3YS7rPq7dAnPBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}