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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bbdcc8a4a18a980a7e54e0e9de82125e80dfd84518c9b1b76881d25de97200c' 
  AND token = 'tZncJJ6abdnxuo+oIac1XBCuA1G8L0AfslOU5YbcJ/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}