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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f47d122d15072dd48c350efe3f0e7d30f8b4efb7a9d172d48ec60885739a2a' 
  AND token = 'S30BEk78/R1r5GcH8BuL5v5PuZmj+UurVMDX9lvVvzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}