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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd083df281e67d77052b8c2326f8b8c7c05c6da9ef9e8dfdc014c5a7d02816c40' 
  AND token = 'hGQt1S7RIzyK4dldzvTvIM7EO2dEUYvyLtQDkEs/qHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}