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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d11e1e879c3e6490a67c716d21d365a84fd484c846a5a114da3e17d0eec11b9' 
  AND token = 'uDOdT+t8kegjXdPfeRRG3paLnqmrPk1bWOlT8x0Y1cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}