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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '169eb0c91e13c82381fe045b9c8e590e1cb0fd8a3eb6ba22f7c310fe45e19757' 
  AND token = 'ZJb/Np0DUsXssrP8q+5lPuCJHhLnlb7xR++9KIiUM8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}