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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5fc7b7cd96498fb78777666e32edb23bd129e1594c0af0d0dc1caaf843fb09f' 
  AND token = 'QMbiu6c+5JumJoBFlbL0RFvUR3gkmonOtlRiC39gWIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}