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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244d3fa06af1e91671c94fd77815fa53e2d52aef51ccd266d499a63a47346642' 
  AND token = 'uTNqaCEed7ZW/JmaqvNAWhciWaYGU2wSUdnt1FATQBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}