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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc257b7ae24222e1f8a4e1bb324b8c466de8a46a89a8a4d885443a20ed045412' 
  AND token = 'ZCTZ0om6BAbZkkXLNUy0q5HqcKr8yPFNuj6tW7KTaxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}