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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49d6f27fd2a9a7a0c279371672cad1d10c58edd14c4653d95259cedd83d9759' 
  AND token = 'l/Dbt2AVn1gw4aF7Y8pgHAiaZmI3s8RvrR9swfVNNTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}