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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8287108186d2792e5b16c3dc9f9333261c61a5c37cb9b77d9d33eec1dceb5aae' 
  AND token = '1+4WsDnSzBEv0iMemoSjnuKLf/wY6LsiLJ73HE4RtQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}