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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7873993f81948495ec465daae051eb7c0b81061d693fb570ba13257e5475bfc3' 
  AND token = 'VLWygXT463j5CgPDb3SDJTVwKyO+N2DEd65XUAW6Lxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}