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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879bed5daa4608635bcb5af7cebbe5ef4e0834eb233980e98035eb6b3b230c0f' 
  AND token = '+7Wjkd5MyUr1OUnt338JBPNgZwsRGYzpGVxg5Zr4ETI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}