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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b02530738b1c40b8bd9a91bdbd5787c993a5e6453da0ff02d4964a57067f6bbe' 
  AND token = 'ymdMY/O0BNvstUn8RFOT6OOGLQ8OiOBHdVlm+aAHZTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}