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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0253dd136b02198f0d8dba9a1a89db9c8e30f351ec972ae6ff68b94c4499ce9b' 
  AND token = 'iRz1EAcrOyUu0tTJyiYX7+bxtZ/jJZ/pwhOnZp1bLZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}