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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b9a060dfc711cc9bcdf9be55cbc856d4fe006fca30de48f6c69997df21a2da' 
  AND token = 'SVqiU8SIT046kkgIE0p8TqpmwvQLwrvqEK8YMthUFxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}