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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad22b04dcd29f9efc218a03636f122ac37f16217c5d26b1cdc5d9a450e407b13' 
  AND token = 'xH6ZTu3acraCZNA2VeqJISeOzfDb2GJokLwjuoR0bFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}