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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f49a610a27d319a1beb507d677f455c61a2c8b2617bb97356df865ed71bcf0e' 
  AND token = '74NBH+EKs7Dv8DMTP1bNlSKn0ay5X0PGMlFRirNou4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}