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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d83ee9e7831069d7a0d08d7e229fc40c0369c40d9b25badb8b4be17a4fb11a' 
  AND token = 'uWfIr1drWaa0XZigbRDFDbzyy5Fd3uLxevFy4NHmZrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}