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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849ed0d7c91382ce5c7c545e1375d35459d262a99ca306adc2c612d695e7afab' 
  AND token = 'DoHCIYXjabXpXxVBc6uE8U42FQWhJngFkK5Lr+JbnP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}