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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86c53e0f9b18377bcfd8ca325a1e53ca29ee809e74360a452841a47c8797aea' 
  AND token = 'VG1Lprd0xkUujjO/CVQ7Mzbb7b/QExscNbtvUUxgYqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}