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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c60249b638e09a5686a34baeae65bf5e70316d0a61d35a19ce1aef6905c978' 
  AND token = '2v6rz3nZkTrH3NYABdPSWU/t/SE0PCDwoScoelJjLBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}