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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6643b5f71b52157ac57055402ef806bc4ec0e54cd59df0ed313cbf57b3ca656a' 
  AND token = 'QCq1+YlSdR2T5QhsHkj3IljuJEoIufJMXGH+ID1oAVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}