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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb35d61f4ad36f81cb8037be5e996df9b0fa93b338c1482f82f5592539095a41' 
  AND token = 'jN9gHgGRB/Ga89Gs+oCoRPT88Ei+zdm63Uh6BoOkGlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}