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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a28df5074a53a2f6fe273b177c40c09ea75468ae1083e41bb1eb38edfd75c4b' 
  AND token = 'Qk6nw97i8ORbjOTwqnM+zmyhMf6G18sdt3qcLi2gsN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}