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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a437680086762d49215daa5a623275b88da8551b22a6b5eb2ce3a49ac1251cd4' 
  AND token = 'T3JlIVp69WRT9i/TcU2ZsI8/hB987Lf45WeqI8otQo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}