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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b59efd35184296afa0b74078d6bafe6b645bfb4a77186ead348718537d67d94' 
  AND token = 'MJXXj5b6b8IIj1IFHCGXgtQAFEO+puj+XZVM2V1OG60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}