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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0a5223ede105d76fcc2c6d49fa5606f75b0742f862bac577935df56f12ec35' 
  AND token = 'qAaCB3B1JMbJcPrnbUJB4dHHBu4eDcCsJKfRI4WOFFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}