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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0010afe6a96e3de4eace09cd3d9976771bf8f00dd25fe4cbb859e1b917d994f7' 
  AND token = 'hupgJtb3uVP7aQXtqNNTbVNeV+u7tjI2YF7LXcItWNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}