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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47079454c159c7851b0446c44d715898a7c50680eb8a177da861589ed7dc7d8a' 
  AND token = 'ROi2rPgj+1HAau0kNeIkPcijxEaQ/XdXvRTFXvWaRFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}