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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f407051a6f5ee568b3e23f0607af0b18b70517cec7ba83728ec8a7f8a34b44f' 
  AND token = 'iq273PCGLhkAyHOrQ88zIMb+zwCzkFaFyfYksKjCq/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}