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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438f21bcfe066799d44e9c9939cf1851b3ce9e5ffa15668136b96de7308ef9ed' 
  AND token = 'KxaBxBygaAIa6F7BvALF1SwWFQHxTJ+RxdP+df1YQ48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}