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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48550cc4c418bca1c9ac8182f5731921b6675bf295a5d6338d661873d803bb9c' 
  AND token = 'mla8HK6Tz0DX7WENZq1KgTDCzy9Tbl6zvj8zFy97eno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}