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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46647352a6ca57c2ad62aac2f7b16865aa88a04811a2ad8b4abcfa1bcd326d78' 
  AND token = '4M7BBCpAQVkKMoy7dX2veNSX/W1j9EV9ubOU0dpPias=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}