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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6874547955bb6e0f2c3dca4a87b12e9c13e0269f4f97dff49afc4fa7f9b00d' 
  AND token = '01RmYER4WvQ4uIUZERPdR2CCl+38Sihu3juS4o/Xf44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}