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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddd1cc685907cbb21fbdbc50a95c9f56fd7817246734a9718863a85e968c0e22' 
  AND token = '/aTPBa5tbv+NuSOlQNNl08ZSoMhBjPfUeI3fmlubmuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}