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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2453196fabec6115168ff29ab34647102379af4b8d7fd84c1e0f4b5ec8fc29b9' 
  AND token = 'eJb6lCoBwIFCDqGwM58OSxITeen6KU704euP6Cg/2Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}