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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051806204d198f45e9161c58d622dc6f21796d79a8c91966016edcce8bc32a5d' 
  AND token = 'VTRXr3V2cWVUmrZOhW9DKSXZhxonxnBsx7jYV7y+/dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}