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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27cd6c06b33be2326eadafc0ee6b68f6d7021c83f3c1c9ae9080dcc74e3ef51' 
  AND token = 'aB7QnuFwpkTC6ZpIq2Vnb6Hr/+VYGgzxau27F6LoyYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}