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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd275b7e723963a7f2aa2f7acb52212c2b89314cd9646d1eeb9a2a8dff2636d48' 
  AND token = 'YVPMV4Q2J5/HFxGjW8rJnOH4nTurFpFZxpPf2fmP2L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}