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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd187b59cd9c91fdc39b35dbe0de7b729bf029f53cbae75c1e0fc2041b8db910c' 
  AND token = 'hbPIlb1s2fOuK1tg2yOPUL9j4+QNyPsvdkWloLW9j3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}