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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467a2060e7d735c9bc715d84afecd086a473fb6a5d42ec609d9cc8836634c4b4' 
  AND token = 'WcrGAP39HwgjrBOYDOc14dSSjgJq/dJ6ikuUWtwKN7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}