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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49908b8c9d78b63a75ad315c49488453fe3e1cec9d1630ac964dda0a5bb9c20' 
  AND token = 'bfvB59Ygp2FmhGLhaYTir160lhaXCX62C/6EdcwQZBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}