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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1d55bb239c876c7ff380e73ff7f084b77d5063f15ebf65938b5c18e3485201' 
  AND token = 'NxwjLlDzr1qWccSH4gcaA2A2xGIupxrty6yJazDAoMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}