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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cff9e0c97b7ed9a8eff8aa5a56efb2565debd933b4650ebea3ae7f8f4f54eaf' 
  AND token = 'TXg2JPLAwGQgL3JB+5znleSHsgh1zcIeVA4m4AmhRiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}