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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfffb3db51ef913319f1eae9f96f07be72352dbdb6047c78b14f18b86af7993c' 
  AND token = 'PhvJTvsQ2yBVnjHU2T+JWhdz6W8Sj3l7TfT9vAgD39c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}