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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21087808ee2f87470df184d519460f0bc2dcd01d2d97b3da5aaa3a211e8e9159' 
  AND token = 'ZL8hj6xlLtnuLuapX6X9/5xIwRtQMrF/LkUOpowRs7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}